According to a new study published on July 7, 2021, the modified ketogenic diet may be worth investigating for people with brain tumors. Neurology.. The diet is high in fat and low in carbohydrates.
A small study found that diet was safe and feasible. Brain tumor It is called an astrocytoma. Everyone has completed radiation therapy and chemotherapy. Diet has changed the metabolism of the body and brain.This study is not designed to determine if eating can be delayed Tumor growth Or improve survival rate.
“There are not many effective treatments for these types of brain tumors. Survival rate Dr. Roy E. Strode, MD, research author at Wake Forest Medical School in Winston Salem, North Carolina, and a fellow at the American Neurological Society said.
“These cancer cells rely on glucose, or sugar, to divide and grow. Ketogenic diet Because of its low sugar content, the body changes what it uses for energy. Instead of carbohydrates, we use so-called ketones.Normal brain cells can survive with ketones, but the theory is cancer cell Ketones cannot be used for energy. “
Twenty-five people with astrocytomas participated in this study. They continued on a modified Atkins diet with intermittent fasting, a type of ketogenic diet, for eight weeks. The diet includes foods such as bacon, eggs, cream, butter, leafy vegetables and fish. Participants met with a dietitian at the beginning of the study and every two weeks thereafter. They changed their Atkins diet five days a week, combining carbohydrate restrictions and large amounts of fat. They fasted two days a week and ate up to 20% of the recommended daily calorie content.
The main purpose of this study was to see if people could follow a diet without serious side effects. Dietary records show that a total of 21 people completed the study and 48% continued their complete diet. However, urinalysis showed that 80% of people have reached levels where they mainly use fat and protein as fuel instead of carbohydrates.
The diet was well tolerated.Two people had Serious side effects During the study, one was unrelated to diet and the other was probably related.
By the end of the study, changes in body and brain metabolism were seen. Hemoglobin A1c levels, insulin levels, and lean body mass were all reduced. I gained lean body mass.Special brain scans that detect changes in brain metabolites showed increased levels of ketones and metabolic changes tumor..
“Of course, more research is needed to determine if this diet can prevent the growth of brain tumors and help people live longer, but these results show: diet Safe for people with brain tumors, with body metabolism brain“Strode said.
The limitation of the study is that members of the research team provided a great deal of contact with the participants, which may not be possible in large-scale studies or routine clinical care.
American Academy of Neurology
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